Novel treatment for cheilitis glandularis.

Sir, In 1870, von Volkmann (1) introduced the term cheilitis glandularis (CG). He described a distinct, chronic inflammatory condition of the lower lip characterized by mucopurulent exudates from the ductal orifices of enlarged labial salivary glands. Historically, CG has been classified into three subtypes: simplex, superficial suppurative, and deep suppurative. However, it is now believed that these represent three stages in progression of a single disease entity. Conventional treatment consists of vermillionectomy or the administration of intralesional corticosteroids. Additional treatment with antibiotics is frequently necessary (2, 3). We report here on a patient with CG treated successfully with a combination of oral minocycline and tacrolimus ointment 0.1%, thereby avoiding invasive therapy.